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Polymyxin B+chloramphenicol+betamethasone

About Polymyxin B+chloramphenicol+betamethasone

Polymyxin B+chloramphenicol+betamethasone belongs to a combination of drugs called antibiotics and corticosteroids used to treat bacterial infections of the ear (otic) and eye (optic). Bacterial eye and ear infections occur when bacteria enter the eye or ear, causing infection. If left untreated, this can lead to conditions like conjunctivitis, otitis externa, and hearing/vision loss.

Polymyxin B+chloramphenicol+betamethasone is a combination of three medicines: Chloramphenicol, Polymyxin B, and Betamethasone. Chloramphenicol and Polymyxin B are antibiotics that work together to kill bacteria and prevent their growth. Betamethasone is a steroid that reduces inflammation, redness, and irritation. Together, they effectively treat and prevent the spread of eye and ear infections caused by bacteria.

Follow your doctor's instructions carefully to use Polymyxin B+chloramphenicol+betamethasone safely and effectively. Common side effects when used in the eyes include eye discomfort, irritation, and a burning sensation. Mild irritation and temporary ear discomfort may occur when used as ear drops. In most cases, these side effects are mild and resolve on their own over time. However, consult your doctor for further guidance if they worsen or persist.

Before using Polymyxin B+chloramphenicol+betamethasone, inform your doctor if you are allergic to foods or medications. Additionally, disclose any pre-existing conditions, such as frequent ear infections, perforated eardrum, recent eye surgery, cataracts, glaucoma, severe nearsightedness, or diabetes. Pregnant or breastfeeding women should consult their doctor before starting Polymyxin B+chloramphenicol+betamethasone. Be cautious when driving after using Polymyxin B+chloramphenicol+betamethasone eye drops, as they may cause temporary blurred vision. Furthermore, Polymyxin B+chloramphenicol+betamethasone should only be used in children under the guidance of a doctor.

Uses of Polymyxin B+chloramphenicol+betamethasone

Polymyxin B+chloramphenicol+betamethasone is used to treat bacterial eye and ear infections.

Medicinal Benefits

Polymyxin B+chloramphenicol+betamethasone offers numerous medicinal benefits, including antibacterial and anti-inflammatory effects, symptom relief, complications prevention, and rapid healing. They effectively combat bacterial infections, reduce inflammation and swelling, and quickly relieve symptoms of bacterial eye and ear infections. Additionally, they help prevent complications such as vision and hearing loss, promote rapid healing, and reduce pain and discomfort. Specifically designed to treat conjunctivitis and otitis media, these drops minimize scarring and promote healthy tissue repair.

Directions for Use

Eye drops: Tilt your head back and pull your lower eyelid downwards and outwards. Gently squeeze the dropper and put the eye drops inside the eye/eyes. Blink a few times to spread the medication inside your eye.

Ear drops: Do not touch the dropper; hold it close to the ear by tilting your head to the side. Gently squeeze the dropper and put the ear drops inside the ear. Keep your head tilted for a minute to let the drops soak in.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Polymyxin B+chloramphenicol+betamethasone

  • Redness in eyes
  • Itching eyes
  • Irritation, burning or stinging sensation
  • Blurred vision
  • Increased sensitivity to light
  • Eyelid swelling

Drug Warnings

Before using, tell your doctor about any allergies or health conditions you have, like ear infections, eye surgery, or diabetes. Pregnant or breastfeeding women should ask their doctor before using. Be careful driving after using eye drops, as they may blur your vision. Children should only use this under a doctor's guidance. Don't touch the tip of the container to keep the medicine clean. Also, don't use any other eye or ear medicines unless your doctor says it's okay.

Drug Interactions

Drug-Drug Interaction: No interactions found.

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have epithelial herpes keratitis, viral diseases of conjunctiva and cornea, fungal diseases of ocular structures, mycobacterial infections of the eye, vaccinia (virus) or varicella (chickenpox), inform your doctor before using Polymyxin B+chloramphenicol+betamethasone. 

Drug-Drug Interactions Checker List:

Safety Advice

  • Safety Warning

    Alcohol

    consult your doctor

    The interaction of alcohol with Polymyxin B+chloramphenicol+betamethasone is unknown. However, it is advisable to limit or avoid alcohol as a precautionary measure.

  • Safety Warning

    Pregnancy

    caution

    There are no adequate and well-controlled studies on pregnant women. Please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

  • Safety Warning

    Breast Feeding

    caution

    Consult your doctor as there is no substantial research yet on the use of Polymyxin B+chloramphenicol+betamethasone in breastfeeding/nursing mothers.

  • Safety Warning

    Driving

    caution

    Polymyxin B+chloramphenicol+betamethasone may cause blurred vision immediately after use. Wait until your vision is clear before driving or operating machinery.

  • Safety Warning

    Liver

    caution

    Limited information is available about using Polymyxin B+chloramphenicol+betamethasone in patients with liver disease. Please consult your physician. Your doctor will weigh the benefits and potential risks before prescribing Polymyxin B+chloramphenicol+betamethasone.

  • Safety Warning

    Kidney

    safe if prescribed

    Limited information is available about using Polymyxin B+chloramphenicol+betamethasone in patients with kidney disease. Please consult your physician. Your doctor will weigh the benefits and potential risks before prescribing Polymyxin B+chloramphenicol+betamethasone.

  • Safety Warning

    Children

    caution

    Polymyxin B+chloramphenicol+betamethasone should be used in children only if prescribed by a doctor.

Habit Forming

No

Diet & Lifestyle Advise

Eye infections:

  • Get at least six to eight hours of sleep each night to renew your eyes.
  • It is recommended that you wash your eyes with clean water at least twice or thrice daily. If you have had eye surgery, wait at least two weeks before washing your eyes.
  • Take care of your health, eat a balanced diet, exercise regularly, and rest well.
  • Regularly wash your hands. Keep unclean hands away from your eyes.
  • Do not rub your eyes.
  • Eyeliner, mascara, and kohl should not be shared.
  • Wipe your eyes and face with clean towels or tissues at all times.
  • If you wear contact lenses, clean and replace them more frequently. Never share your contact lenses. Always wash your hands before and after inserting and removing them.
  • Avoid gazing at digital screens for extended periods.
  • Blink frequently to aid in the spread of hydrating substances like mucus and tears across the eyes.

Ear infections:

  • Immunity helps prevent infection. To strengthen your immune system, eat fruits and vegetables, high-quality proteins, and whole wheat grains.
  • Avoid consuming foods you are allergic to, as they can cause the body to produce excessive mucus, which can result in inflammation.
  • Avoid getting shampoo, soap, and water in the ear because they can cause itching.
  • Poking or scratching the ear can cause damage to the ear canal, resulting in inflammation.
  • Quit or limit the intake of caffeine and alcohol.

Special Advise

Patients Concern

Disease/Condition Glossary

Bacterial eye and ear infections occur when bacteria enter the eye or ear, causing inflammation, damage, and potentially serious complications. In the eye, bacterial infections can lead to conditions such as conjunctivitis, blepharitis, and keratitis, causing symptoms like redness, itching, discharge, and blurred vision. In the ear, bacterial infections can cause otitis externa, otitis media, and otitis interna, resulting in symptoms like ear pain, fever, discharge, and hearing loss. Bacterial eye and ear infections can lead to serious complications, including vision loss, hearing loss, and even life-threatening conditions.

FAQs

Polymyxin B+chloramphenicol+betamethasone is used to treat bacterial eye and ear infections.

Polymyxin B+chloramphenicol+betamethasone contains Chloramphenicol, Betamethasone, and Polymyxin B. Chloramphenicol is an antibiotic that interferes with the formation of essential proteins required for bacterial growth. Betamethasone is a steroid that reduces inflammation and symptoms associated with infection, such as redness and irritation. Polymyxin B is bactericidal, which kills the bacterial cell and prevents the formation of bacterial cell walls, which is essential for survival. Therefore, it treats eye/ear infections.

It's recommended to avoid wearing contact lenses while using Polymyxin B+chloramphenicol+betamethasone, especially if you have an active eye infection, as it may interact with lenses or slow down healing. Consult your doctor or pharmacist for personalized advice.

Maintaining a minimum of 10-minute time gap between using Polymyxin B+chloramphenicol+betamethasone and other eye drops and administering eye ointments in the last is advised.

Yes, Polymyxin B+chloramphenicol+betamethasone may temporarily blur your vision. Therefore, wait until your vision is clear before driving or operating heavy machinery.

No, do not stop using Polymyxin B+chloramphenicol+betamethasone without consulting your doctor or pharmacist. Stopping the medication abruptly may lead to a relapse of the infection or reduce the effectiveness of the treatment. Always follow the recommended treatment duration and consult your healthcare professional if you have any concerns.

No, Polymyxin B+chloramphenicol+betamethasone is not recommended for eye ulcers. It's specifically designed to treat bacterial eye and ear infections, such as conjunctivitis and otitis media. You should consult your doctor or pharmacist for a suitable treatment option for eye ulcers.

Polymyxin B+chloramphenicol+betamethasone is generally safe when used as directed. However, prolonged or improper use can increase the risk of complications, including vision problems. If you experience any vision changes, eye pain, or increased sensitivity to light, discontinue use and consult your doctor immediately.

Yes, Polymyxin B+chloramphenicol+betamethasone contains antibiotics, specifically Chloramphenicol and Polymyxin B, which help combat bacterial infections in the eyes and ears.

Polymyxin B+chloramphenicol+betamethasone should be stored in a cool and dry place away from sunlight. Keep out of reach of children.

If you accidentally apply an excess of Polymyxin B+chloramphenicol+betamethasone, immediately flush your eyes or ears with water. Remove any contact lenses, if applicable. If irritation persists, consult your doctor for advice.

Common side effects of Polymyxin B+chloramphenicol+betamethasone may include redness, itching, irritation, burning or stinging sensation, blurred vision, sensitivity to light, eyelid swelling, itching or crusting. Most of these side effects are mild and temporary, resolving on their own over time. However, if any of these side effects worsen or persist, consult your doctor for advice.

Available Medicines for

Polymyxin B+chloramphenicol+betamethasone

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